Decision Lab at UCSF (Chiong lab)

expressionist art representing The dissonance between individuality and commonality, between the self as unique and life as patterned with warm colors

Spetz J, Wagner LM, White EM, Chapman SA, Chiong W, Friedman EM, Gerlach LB, Harrison KL, Hunt LJ, Lee SJ, Muench U, Possin K, Sideman A, Hickey JVTS, Putthinun P, Yeh J, Sandoval S, Rose A, Rothstein J, Pettit AR, Maust DT, Zimmerman S.
The National Dementia Workforce Study: development of questionnaires for home care, assisted living, and nursing home settings

Journal of the American Geriatrics Society. 2025;2.10

Open Access
PubMed Central PMC12407246
10.1111/jgs.70048

Two hands holding, one has a gold wedding band.

Hunt LJ, Harrison KL, Kiekhofer R, Merrilees J, Sideman AB, Dulaney S, Allen IE, Lee K, Chiong W, Hooper SM, Bonasera SJ, Braley TL, Miller BL, Possin KL.
The effect of the Ecosystem collaborative model on end-of-life outcomes for people with dementia and their givers

American Journal of Hospital Palliative Medicine. 2025;0(0).

10.1177/10499091251367311

White EM, Wagner J, Stewart K, Guyer H, Nelson S, Chiong W, Muench U, Sideman A, Gerlach LB, Possin K, Pettit AR, Rothstein J, Marcus SC, Spetz J, Maust DT.
The National Dementia Workforce Study: Methods for surveying community clinicians who provide to people with dementia.

Journal of the American Geriatrics Society. 2025;1-9.

Open Access
10.1111/jgs.70037

Figure 1. Evolution of left orbitofrontal cavernous malformation.

Schwartz NU, Dietz CD, Prufer Araújo I, Villanueva-Meyer JE, Chiong W, Lane-Donovan C, Vandevrede L, Ljubenkov PA, Wang Y, Soleimani-Meigooni DN, La Joie R, Rojas JC. Guterman EL.
Changes of a cerebral cavernous malformation associated with lecanemab therapy in a patient with Alzheimer disease.

Neurology Clinical Practice 2025 Aug;15(4):e200508.

Open Access
PubMed Central PMC12204771
10.1212/CPJ.0000000000200508

Figure one, Distribution of COST scores by race and ethnicity. COST = COmprehensive Score for financial Toxicity.

Hart DM, Leggins B, Sanches C, Guterman EL, Chiong W.
Financial toxicity in dementia giving: Sociodemographic predictors in a U.S. nationally representative survey.

Gerontologist. 2025; 65(6):gnaf092.

PubMed Central PMC12065397
10.1093/geront/gnaf092
Preregistration
Open Data
Open Materials

A tailor taking measurements of a client

Brown JEH, Chiong W, Hutchinson N.
Integrating n-of-1 trials into learning health care systems.

JAMA Neurology. 2025; 82(5):431-432.

PubMed Central PMC12068953
10.1001/jamaneurol.2024.4674

'Woodstock'. Rice bran oil bubbles floating on water over a reflective surface, producing a psychedelic effect.

Matvey M, Kelley DP, Bradley ER, Chiong W, O’Donovan A, Woolley J.
Modifying informed consent to help address functional unmasking in psychedelic clinical trials.

JAMA Psychiatry. 2025; 82(3):311-318.

10.1001/jamapsychiatry.2024.4312

Figure 1 of paper: Survey Weighted Proportions of US Adults' Preferences and Perceptions Regarding Closed-Loop Brain Implants.

Chen BB, Haeusermann T, Dada A, Hamilton RH, James JE, Fong KC, Dohan D, Chiong W.
Race-ethnicity, rurality, and age in prospective preferences and concerns regarding closed-loop implanted neural devices.

Journal of Neuropsychiatry and Clinical Neurosciences. 2025;37(1):79-87.

PubMed Central PMC11969628
10.1176/appi.neuropsych.20230190
Preregistration
Open Data
Open Materials

Fig. 1 Survey weighted proportions of U.S. dementia caregivers’ willingness to participate in a hypothetical dementia clinical trial with their care recipient

Leggins B, Hart DM, Jackson AJ, Levenson RW, Windon CC, Merrilees J, Chiong W.
Perceptions about dementia clinical trials among underrepresented populations: A nationally representative survey of U.S. dementia caregivers.

Alzheimers Research & Therapy. 2024;16(1):224.

Open Access
PubMed Central PMC11476697
10.1186/s13195-024-01579-5
Preregistration
Open Data

Figure 1. Mr. U’s brain volumes compared to healthy controls.

Antoniou R, Callahan P, Kramer JH, Miller BL, Chiong W, Rankin KP.
Socioemotional dysfunction and the greater good: a case study.

Neurocase. 2024;30(4):125-134.

PubMed Central PMC11604522
10.1080/13554794.2024.2404682

a crystal ball on top of golden-yellow velour-like fabric against a deep blue background.

Hoy CW, Chiong W.
The ethical landscape of prodromal Parkinson disease: Considerations for shared decision-making and health equity.

Neurology. 2024; 102(11):e209522.

PubMed Central PMC10700017
10.1212/WNL.0000000000209522

A grid showing six scans of grey matter in brains. Figure 3 from the article that is linked.

Ngo S, Jackson AJ, Manivannan M, Young JC, Leggins B, Cryns NG, Tran ST, Grant HE, Knudtson MV, Chiong W.
Real world financial mismanagement in Alzheimer's disease, frontotemporal dementia, and primary progressive aphasia.

Journal of Alzheimer’s Disease. 2024; 99(1):251-262.

PubMed Central PMC11132181
10.3233/JAD-231021
Preregistration
Open Materials

Haeusermann T꙳, Liu EY꙳, Fong KC, Dohan D, Chiong W. ꙳(co-first authors)
Patient experiences of resection versus responsive neurostimulation for drug-resistant epilepsy.

Epilepsy & Behavior. 2024; 153:109707.

Open Access
PubMed Central PMC11185832
10.10.1016/j.yebeh.2024.109707

a large pile of medicinal pills in various sizes, shapes, and colors.

Haeusermann T, Chiong W.
Ethical considerations in rapid and novel treatments in psychiatry.

Neuropsychopharmacology. 2024; 49(1):291-293.

Open Access
PubMed Central PMC10700644
10.1038/s41386-023-01635-y

the back of a person's head who appears to be an adult with short brown hair. They are gazing at an electronic screen that reads 'Then how did he know your name'.

Sankaran N, Moses D, Chiong W, Chang EF.
Recommendations for promoting user agency in the design of speech neuroprostheses.

Frontiers in Human Neuroscience. 2023;17:1298129.

Open Access
PubMed Central PMC10619159
10.3389/fnhum.2023.1298129

A graph showing 'Change Relative to Baseline in Mean Monthly Total Cost of Care Among Patients With 24-Month Continuous Medicare Fee-for-Service Coverage'. Figure 2 from the article that is linked.

Guterman EL, Kiekhofer RE, Wood AJ, Allen IE, Kahn JG, Dulaney S, Merrilees JJ, Lee K, Chiong W, Bonasera SJ, Braley TL, Hunt LJ, Harrison KL, Miller BL, Possin KL.
Care Ecosystem collaborative model and health care costs in Medicare beneficiaries with dementia: A secondary analysis of a randomized clinical trial.

JAMA Internal Medicine. 2023; 183(11):1222-1228.

PubMed Central PMC10507595
10.1001/jamainternmed.2023.4764

Two side-by-side round white pills dissolving in deep blue-colored water.

Hoy CW, Chiong W.
Book Review: DeGrazia D, Millum J. A Theory of Bioethics. Cambridge University Press. 2021.

Kennedy Institute of Ethics Journal. 2023; 33(3):321-325.

10.1353/ken.2023.a917931

3D medical brain scan showing two views of a yellow brain region with surrounding vasculature and a surgical needle approach path.

Hoy CW, Little SJ, Chiong W.
Using neuroscientific and clinical context to assess and manage changes in core personal traits caused by deep brain stimulation.

AJOB Neuroscience. 2023; 14(3):310-312.

PubMed Central PMC10700017
10.1080/21507740.2023.2243873

Table 2. Across-group comparisons of emotion elicitation during moral reasoning. Absolute frequencies and proportions after normalization.

Antoniou R, Haeusermann T, Bernstein Sideman A, Fong KC, Callahan P, Miller BL, Kramer KL, Chiong W, Rankin KP.
Moral reasoning through the eyes of persons with behavioral variant frontotemporal dementia.

Frontiers in Neurology. 2023; 14:1197213.

Open Access
PubMed Central PMC10365271
10.3389/fneur.2023.1197213

Figure 2 of paper: Revised two-dimensional model of utilitarian judgment.

Antoniou R, Romero-Kornblum H, Young CJ, You M, Kramer JH, Rankin KP, Chiong W.
Contrasting two models of utilitarian reasoning.

Heliyon. 2023; 9(7):e17498.

Open Access
PubMed Central PMC10328838
10.1016/j.heliyon.2023.e17498
Preregistration
Open Data

Figure 1 of paper: open-loop and closed-loop neuromodulation.

Haeusermann T, Lechner CR, Fong KC, Bernstein Sideman A, Jaworska A, Chiong W, Dohan D.
Closed-loop neuromodulation and self-perception in clinical treatment of refractory epilepsy.

AJOB Neuroscience. 2023;14(1):32-44.

Open Access
PubMed Central PMC9007331
10.1080/21507740.2021.1958100

Two people share a warm embrace and kiss beside a calm canal on a cool day. One person wears a black jacket and glasses, the other a red puffer vest and teal knit hat. A colorful narrowboat is moored along the tree-lined waterway behind them.

Sideman AB, Merrilees J, Dulaney S, Kiekhofer R, Braley T, Lee K, Chiong W, Miller B, Bonasera SJ, Possin KL.
''Out of the clear blue sky she tells me she loves me'': Connection experiences between caregivers and people with dementia.

Journal of the American Geriatric Society. 2023; 71(7):2172-2183.

PubMed Central PMC10500033
10.1111/jgs.18297

Figure 3 of paper: Flowchart of the Care Ecosystem Medication Review Intervention and Monitoring Process.

Liu AK, Possin KL, Cook KM, Lynch S, Dulaney S, Merrilees JJ, Braley T, Kiekhofer RE, Bonasera SJ, Allen IE, Chiong W, Clark AM, Feuer J, Ewalt J, Guterman EL, Gearhart R, Miller BL, Lee KP.
Effect of collaborative dementia care on potentially inappropriate medication use: Outcomes from the Care Ecosystem randomized clinical trial.

Alzheimer’s & Dementia. 2023; 19(5):1865-1875.

PubMed Central PMC10156873
10.1002/alz.12808

A healthcare worker in scrubs sitting on the floor of a hospital corridor, leaning against the wall.

Haeusermann T, Romero-Kornblum H, Dzeng E.
Of care, cure and the in-between: COVID-19 treatment in a New York City intensive care unit

International Journal of Care and Caring. 2022; 6(1-2):67-84.

10.1332/239788221X16316503274460

Figure 1 of paper: Conceptual model of relationships among financial activity, mismanagement and abuse in dementia.

Manivannan M, Heunis J, Hooper SM, Bernstein Sideman A, Lui KP, Possin KL, Chiong W.
Use of telephone- and internet-based support to elicit and address financial abuse and mismanagement in dementia: Experiences from the Care Ecosystem study.

Journal of Alzheimer’s Disease. 2022; 86(1):219-229.

PubMed Central PMC10938943
10.3233/JAD-215284

A close-up of an IV drip chamber and fluid bag on a medical pole.

Chiong W, Tolchin BD, Bonnie RJ, Busl K, Cruz-Flores S, Epstein LG, Greene EP, Illes J, Kirschen M, Larriviere DG, Mantri S, Rubin MA, Stern BJ, Taylor LP, on behalf of the Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society).
Decisions with patients and families regarding aducanumab in Alzheimer disease, with recommendations for consent: AAN position statement.

Neurology. 2022; 98(4):154-159.

Open Access
10.1212/WNL.0000000000013053

Two cerebral angiography images labeled A and B, showing blood vessel structure in the brain before and after a procedure.

Sattin JA, Chiong W, Bonnie RJ, Kirschen MP, Russell JA, on behalf of the Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society).
Consent issues in the management of acute ischemic stroke: AAN position statement.

Neurology. 2022; 98(2):73-79.

10.1212/WNL.0000000000013040

Figure 2:. The Relationship between Processing Speed and Wisdom.

Lindbergh CA, Romero-Kornblum H, Weiner-Light S, Young JC, Fonseca C, You M, Wolf A, Staffaroni AM, Daly R, Jeste DV, Kramer JH, Chiong W, the Hillblom Aging Network.
Wisdom and fluid intelligence are dissociable in healthy older adults.

International Psychogeriatrics. 2022; 34(3):229–239.

Open Access
PubMed Central PMC8578582
10.1017/S1041610221000521
Preregistration
Open Data

Close up of two people shaking hands against a white background.

Jaworska A, Chiong W.
Supported decision-making for people with dementia should focus on their values.

American Journal of Bioethics. 2021; 21(11):19–21.

Open Access
10.1080/15265161.2021.1980150

Figure 2 of paper: Utilitarian responses and personal rights dilemmas.

Antoniou R, Romero-Kornblum H, Young JC, You M, Kramer JH, Chiong W.
Reduced utilitarian willingness to violate personal rights during the COVID-19 pandemic.

PLoS One. 2021; 16(10):e0259110.

Open Access
PubMed Central PMC8535394
10.1371/journal.pone.0259110
PsyArXiv preprint
Preregistration
Open Data
Open Materials

An illustration showing two people against a light blue background. A younger person in a teal shirt leans in attentively, resting a hand on the shoulder of an older person with a white beard who is bent slightly forward.

Ma H, Kiekhofer RE, Hooper SM, Dulaney S, Possin KL, Chiong W.
Goals of care conversations and subsequent advance care planning outcomes for people with dementia.

Journal of Alzheimer’s Disease. 2021; 83(4):1767–1773.

PubMed Central PMC9034733
10.3233/JAD-210720

Blister packs of pills resting on a spread of banknotes.

Ngo S, Kim AS, Chiong W.
Evidence for the ethics of incentivizing clinical trial enrollment?

JAMA Internal Medicine. 2021; 181(11):1488-1489.

10.1001/jamainternmed.2021.5449

Illustration of a brain split in two halves, one depicting a circuit board and the other organic brain matter, symbolizing artificial versus human intelligence.

Chiang S, Picard RW, Chiong W, Moss R, Worrell GA, Rao VR, Goldenholz DM.
Guidelines for conducting ethical artificial intelligence research in neurology: A systematic approach for clinicians and researchers.

Neurology. 2021; 97(13):632–640

PubMed Central PMC8480407
10.1212/WNL.0000000000012570

Black and white portrait of an elderly woman smiling warmly, wearing a knit hat.

Chiong W, Tsou AY, Simmons Z, Bonnie RJ, Russell JA, on behalf of the Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society).
Ethical considerations in dementia diagnosis and care: AAN position statement.

Neurology. 2021; 97(2):80-89.

10.1212/WNL.0000000000012079

A young child sitting up in a hospital bed, wearing a white head bandage and a colorful plaid shirt, reaches out with an excited expression.

Hrincu V, McDonald PJ, Connolly MB, Harrison MJ, Ibrahim GM, Naftel RP, Chiong W, Alam A, Ribary U, Illes J.
Choice and trade-offs: parent decision making for neurotechnologies for pediatric drug-resistant epilepsy.

Journal of Child Neurology. 2021; 36(11):943-949.

PubMed Central PMC8458226
10.1177/08830738211015010

Figure of paper: Responsive Neurostimulation System.

Hegde M, Chiong W, Rao VR.
New ethical and clinical challenges in “closed-loop” neuromodulation.

Neurology. 2021; 96(17):799-804.

PubMed Central PMC8166428
10.1212/WNL.0000000000011834

Surgical instruments and a stereotactic frame positioned on a patient's head during a neurosurgical procedure

Mergenthaler JV, Chiong W, Dohan D, Feler J, Lechner CR, Starr PA, Arias JJ.
A qualitative analysis of ethical perspectives on recruitment and consent for human intracranial electrophysiology studies.

AJOB Neuroscience. 2021; 12(1):57-67.

PubMed Central PMC8168380
10.1080/21507740.2020.1866098

Figure 1 of paper: An objective attitude is associated with decreased relationship closeness between care-giver and care-recipient while not protecting against care-giver strain.

Zahir A, Staffaroni AM, Wickham RE, Quinn CM, Sapozhnikova A, Seidman J, Chiong W.
Caregiver “objective attitude” toward patients with neurodegenerative disease: Consequences for caregiver strain and relationship closeness.

Aging & Mental Health. 2021; 25(9):1709–1715.

PubMed Central PMC7748409
10.1080/13607863.2020.1771541

A person writing a checklist in a notebook with a pen.

Fong KC, Chiong W.
Understanding advance directives as a component of advance care planning.

American Journal of Bioethics. 2020; 20(8):67-69.

10.1080/15265161.2020.1781974

Two healthcare or laboratory workers in full PPE, including hazmat suits, face shields, and gloves, working together in a clinical setting.

Goss AL, Chiong W, Hemphill JC.
Neurologists' duties in planning for triage of critical care resources in the COVID-19 pandemic.

Annals of Neurology. 2020; 88(3):431-432.

Open Access
PubMed Central PMC7405081
10.1002/ana.25852

Warm sunlight streaming through large windows into a softly lit room.

Chiong W.
Insiders and outsiders: Lessons for neuroethics from the history of bioethics.

AJOB Neuroscience. 2020; 11(3):155-166.

Open Access
PubMed Central PMC7485591
10.1080/21507740.2020.1778118

Three women of different generations smiling outdoors.

Bernstein A, Merrilees J, Dulaney S, Harrison KL, Chiong W, Ong P, Heunis J, Choi J, Walker R, Feuer JE, Lee K, Dohan D, Bonasera SJ, Miller BL, Possin KL.
Using care navigation to address caregiver burden in dementia: A qualitative case study analysis.

Alzheimer’s & Dementia. 2020; 6(1):e12010.

Open Access
PubMed Central PMC7201177
10.1002/trc2.12010

Figure 3 of paper: The proportion of trials in which smaller immediate reward was chosen.

Beagle AJ, Zahir A, Borzello M, Kayser AS, Hsu M, Miller BL, Kramer JH, Chiong W.
Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.

Cortex. 2020; 124:54-65.

PubMed Central PMC7060812
10.1016/j.cortex.2019.10.009
Open Data
Open Materials

A black and white close-up photograph of a young child looking on as a gloved healthcare worker administers an injection or vaccination to their arm.

Haeusermann T, Fong KC, Lechner CR.
Book Review: Lynch, JA. The Origins of Bioethics: Remembering When Medicine Went Wrong. Michigan State University Press. 2019. 228pp. ISBN 9781611863413.

Sociology of Health & Illness. 2020; 42(4):962-963.

10.1111/1467-9566.13060

Merrilees JJ, Bernstein A, Dulaney S, Heunis J, Walker R, Rah E, Choi J, Gawlas K, Carroll S, Ong P, Feuer J, Braley T, Clark AM, Lee K, Chiong W, Bonasera SJ, Miller BL, Possin KL.
The Care Ecosystem: Promoting self-efficacy among dementia family caregivers.

Dementia. 2020; 19(6)1955-1973.

PubMed Central PMC6541533
10.1177/1471301218814121

Green, yellow, red, and blue 3-dimensional wooden blocks on a flat surface.

Chiong W, Haeusermann T.
Commentary 1: Researcher integrity and contrasting obligations in interdisciplinary research.

Journal of Empirical Research on Human Research Ethics. 2019; 14(5):487-489.

PubMed Central PMC6980360
10.1177/1556264619853198a

Figure 1 of paper: Potential paths for neural devices and implications for post-trial access and maintenance.

Hendriks S, Grady C, Ramos KM, Chiong W, Fins JJ, Ford P, Goering S, Greely HT, Hutchison K, Kelly ML, Kim SYH, Klein E, Lisanby SH, Mayberg H, Maslen H, Miller FG, Rommelfanger K, Sheth SA, Wexler A.
Ethical challenges of risk, informed consent, and posttrial responsibilities in human research with neural devices: A review.

JAMA Neurology. 2019; 76(12):1506-1514.

PubMed Central PMC9395156
10.1001/jamaneurol.2019.3523

Figure 3 of paper: Zip codes of persons with dementia enrolled in the care ecosystem trial.

Possin KL, Merrilees JJ, Dulaney S, Bonasera SJ, Chiong W, Lee KP, Hooper SM, Allen IE, Braley T, Bernstein A, Rosa TD, Harrison K, Begert-Hellings H, Kornak J, Kahn JG, Naasan G, Lanata S, Clark AM, Chodos A, Gearhart R, Ritchie C, Miller BL.
Effect of collaborative dementia care via telephone and internet on quality of life, caregiver well-being, and health care use: The Care Ecosystem randomized clinical trial.

JAMA Internal Medicine. 2019; 179(12):1658-1667.

Open Access
PubMed Central PMC6777227
10.1001/jamainternmed.2019.4101

Figure 2. Differences in gambling frequency between Loss and Gain Frame.

Quinn CM, Borzello M, Zahir A, Kramer JH, Chiong W.
COMT Val158Met polymorphism associated with greater susceptibility to framing effects in healthy older adults.

bioRxiv. 2019. [unrefereed preprint]

10.1101/790808
bioRxiv preprint

A grid of four microscopy images showing stained brain or tissue samples.

Butler PM, Chiong W.
Neurodegenerative disorders of the human frontal lobes.

Handbook of Clinical Neurology. 2019; 163:391-410.

10.1016/B978-0-12-804281-6.00021-5

Variations in costs of a collaborative care model for dementia.

Rosa TD, Possin KL, Bernstein A, Merrilees J, Dulaney S, Matuoka J, Lee KP, Chiong W, Bonasera SJ, Harrison KL, Kahn JG.
Variations in costs of a collaborative care model for dementia.

Journal of the American Geriatrics Society. 2019; 67(12):2628-2633.

PubMed Central PMC6898731
10.1111/jgs.16076

A young woman wearing headphones working at a laptop in an office or study setting.

Bernstein A, Harrison KL, Dulaney S, Merrilees J, Bowhay A, Heunis J, Choi J, Feuer JE, Clark AM, Chiong W, Lee K, Braley TL, Bonasera SJ, Ritchie C, Dohan D, Miller BL, Possin KL.
The role of care navigators working with people with dementia and their caregivers.

Journal of Alzheimer’s Disease. 2019; 71(1):45-55.

PubMed Central PMC7004209
10.3233/JAD-180957

A hospital directional sign pointing to the Emergency department and hospital entrance on 17th Street S.

Guterman EL, Allen IE, Josephson SA, Merrilees JJ, Dulaney S, Chiong W, Lee K, Bonasera SJ, Miller BL, Possin KL.
Association between caregiver depression and emergency department use among patients with dementia.

JAMA Neurology. 2019; 76(10):1166-1173.

Open Access
PubMed Central PMC6618767
10.1001/jamaneurol.2019.1820

Empty hospital bed with a white pillow and blue bedding against a dark teal wall.

Chen Y, Wilson L, Kornak J, Dudley RA, Merrilees J, Bonasera SJ, Byrne CM, Lee K, Chiong W, Miller BL, Possin KL.
The costs of dementia subtypes to California Medicare fee-for-service, 2015.

Alzheimer’s & Dementia. 2019; 15(7): 899-906.

PubMed Central PMC7183386
10.1016/j.jalz.2019.03.015

Figure 4. Neuroimaging results showing brain activation maps for the main effect of moral versus non-moral processing

Thomas ML, Martin AS, Eyler L, Lee EE, Macagno E, Devereaux M, Chiong W, Jeste DV.
Individual differences in level of wisdom are associated with brain activation during a moral decision‐making task.

Brain and Behavior. 2019; 9(6):e01302.

Open Access
PubMed Central PMC6577614
10.1002/brb3.1302

Figure 2. Regions where DRD4 dampened function is associated with greater atrophy in FTD with results nested in FTD versus control atrophy maps.

Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW.
Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia.

NeuroImage. Clinical. 2019; 23:101822.

Open Access
PubMed Central PMC6475809
10.1016/j.nicl.2019.101822

Ramos KM, Grady C, Greely HT, Chiong W, Eberwine J, Farahany NA, Johnson LS, Hyman SE, Rommelfanger KS, Serrano EE, Churchill JD, Gordon JA, Koroshetz WJ.
The NIH BRAIN initiative: Integrating neuroethics and neuroscience.

Neuron. 2019; 101(3):394-398.

Open Access
10.1016/j.neuron.2019.01.024

Greely HT, Grady C, Ramos KM, Chiong W, Eberwine J, Farahany NA, Johnson LS, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE.
Neuroethics guiding principles for the NIH BRAIN initiative.

Journal of Neuroscience. 2018; 38(50):10586-10588.

Open Access
PubMed Central PMC6297371
10.1523/JNEUROSCI.2077-18.2018

Vaishnav NH, Chiong W.
Informed consent for the human research subject with a neurologic disorder.

Seminars in Neurology. 2018; 38(5):539-547.

10.1055/s-0038-1668077

Figure 2. Dimensions of ethical scrutiny.

Chiong W, Leonard MK, Chang EF.
Neurosurgical patients as human research subjects: Ethical considerations in intracranial electrophysiology research.

Neurosurgery. 2018; 83(1):29-37.

PubMed Central PMC5777911
10.1093/neuros/nyx361

A side-by-side comparison of two axial PET scan brain scans using a heat map color scale, where blue and green indicate lower metabolic activity and yellow and red indicate higher activity.

Chiong W.
Challenges in communicating and understanding predictive biomarker imaging for Alzheimer disease.

JAMA Neurology. 2018; 75(1):18-19.

10.1001/jamaneurol.2017.2558

Diagram illustrating the Care Ecosystem Dementia Specialist Team model, showing the relationships between the patient/caregiver dyad, a care team navigator, and surrounding support roles.

Possin KL, Merrilees J, Bonasera SJ, Bernstein A, Chiong W, Lee K, Wilson L, Hooper SM, Dulaney S, Braley T, Laohavanich S, Feuer JE, Clark AM, Schaffer MW, Schenk AK, Heunis J, Ong P, Cook KM, Bowhay AD, Gearhart R, Chodos A, Naasan G, Bindman AB, Dohan D, Ritchie C, Miller BL.
Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem.

PLoS Medicine. 2017; 14(3):e1002260.

Open Access
PubMed Central PMC5360211
10.1371/journal.pmed.1002260